LITT technology involves heating intracranial lesion tissues using lasers to achieve thermal ablation. When the temperature is below 43°C, there is no tissue damage. At 45-50°C, short-term reversible damage occurs, while prolonged exposure leads to irreversible damage. At 50-60°C, irreversible damage can be achieved within a few minutes. Temperatures between 60-90°C result in instantaneous cellular inactivation, achieving the desired therapeutic effect. Temperatures exceeding 100°C can cause intense vaporization, carbonization, or even melting. Therefore, during LITT procedures, real-time magnetic resonance guidance is used to control the core temperature of the ablation area within the range of 60-90°C, ensuring stable and controlled thermal ablation for therapeutic efficacy.

The magnetic resonance-guided laser ablation therapy system utilizes scattered fiber optic cables to deliver laser energy, enabling uniform ablation of the lesion. The scattered fiber optic cables are placed within a cooling sleeve, and a water cooling system is employed to ensure controlled core temperature.

The LITT procedure is performed under real-time monitoring of magnetic resonance imaging (MRI). Protons at different temperatures exhibit varying distances of motion under MRI and can be scanned using specific imaging sequences. Through software algorithms, the protons' behavior is identified and processed in real-time, providing feedback to the user. The temperature measurement error is less than 1°C. This technology is internationally leading, with multiple invention patents and complete intellectual property rights.